School of Biology current student

Information for current students at the School of Biology

Biology Online Module Handbook

BL4220 Molecular Mechanisms of Degenerative Diseases

(BL4220 online module handbook version )

cover image
Degenerative diseases, including ALS and SMA are life-limiting conditions, with few treatment options and no definitive cures. While the genetic causes are, in some cases, known, the molecular mechanisms leading to cellular damage are not understood. This module will focus on what is known about the cellular pathology of these conditions with an emphasis on the physical organisation of mammalian cells and RNA biology. Recently developed treatment options will be discussed. The module will also touch on the real-life experiences of people living with degenerative conditions or working directly with them.*

Credits: 15*

Semester: 2

Module Organiser
Dr Judith Sleeman
jes14@st-andrews.ac.uk
01334 463524
Pre-requisite Modules:
Before taking this module you must pass BL3302 or pass BL2301 or pass BL2302*
Anti-requisite Modules:
*
Post-requisite Modules:
*
Additional Module Information:


Biology Teaching Office:
Level 2, Biomolecular Sciences Building, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST

Email: bioteach@st-andrews.ac.uk      Phone: +44 (0)1334 46 3602 or 3566

BL4220: Timetable

Legend (not all modules have every event type):
lecture
tutorial
workshop
practical
other

Semester 2: Week 1

DATE & TIMEVENUESTAFFEVENT
Friday
19-01-2024
15:00 to 16:00
Biomolecular Sciences Building
Seminar Room
Dr Judith Sleeman
-
Lecture L1: Module introduction
2023-4_BL4220_L1
Friday
19-01-2024
16:00 to 17:00
Biomolecular Sciences Building
Seminar Room
Dr Judith Sleeman
-
Workshop W1: Paper Analysis
2023-4_BL4220_W1

Semester 2: Week 2

DATE & TIMEVENUESTAFFEVENT
Friday
26-01-2024
15:00 to 16:00
Biomolecular Sciences Building
Seminar Room
Dr Gareth Miles
-
Lecture L2: Motor Neurons: Function and Dysfunction
2023-4_BL4220_L2
Friday
26-01-2024
16:00 to 17:00
Biomolecular Sciences Building
Seminar Room
jv32
-
Lecture L3: Protein aggregation in neurodegeneration
2023-4_BL4220_L3

Semester 2: Week 3

DATE & TIMEVENUESTAFFEVENT
Friday
02-02-2024
15:00 to 16:00
Biomolecular Sciences Building
Seminar Room
Dr Judith Sleeman
-
Lecture L4: Gene Expression Overview i
2023-4_BL4220_L4
Friday
02-02-2024
16:00 to 17:00
Biomolecular Sciences Building
Seminar Room
Dr Judith Sleeman
-
Lecture L5: Gene Expression Overview ii
2023-4_BL4220_L5

Semester 2: Week 4

DATE & TIMEVENUESTAFFEVENT
Friday
09-02-2024
15:00 to 17:00
Biomolecular Sciences Building
Seminar Room
Dr Judith Sleeman
-
Workshop W2: Student Paper Analyses 1 and 2
2023-4_BL4220_W2

Semester 2: Week 5

DATE & TIMEVENUESTAFFEVENT
Friday
16-02-2024
15:00 to 17:00
Biomolecular Sciences Building
Seminar Room
Dr Judith Sleeman
-
Workshop W3: Student Paper Analyses 3 and 4
2023-4_BL4220_W3

Semester 2: Week 6

DATE & TIMEVENUESTAFFEVENT
Friday
23-02-2024
15:00 to 17:00
Biomolecular Sciences Building
Seminar Room
Dr Judith Sleeman
-
Other O1: Living with degenerative conditions
2023-4_BL4220_O1

Spring Break: 26-Feb-2024 to 01-Mar-2024

Semester 2: Week 7

DATE & TIMEVENUESTAFFEVENT
Friday
08-03-2024
15:00 to 17:00
Biomolecular Sciences Building
Seminar Room
Dr Judith Sleeman
-
Workshop W4: Student Paper Analyses 5 and 6
2023-4_BL4220_W4

Semester 2: Week 8

DATE & TIMEVENUESTAFFEVENT
Friday
15-03-2024
15:00 to 17:00
Biomolecular Sciences Building
Seminar Room
Dr Judith Sleeman
-
Workshop W5: Student Paper Analyses 7 and 8
2023-4_BL4220_W5

Semester 2: Week 9

DATE & TIMEVENUESTAFFEVENT
Friday
22-03-2024
15:00 to 17:00
Biomolecular Sciences Building
Seminar Room
Dr Judith Sleeman
-
Workshop W6: Student Paper Analyses 9 and 10
2023-4_BL4220_W6

Semester 2: Week 10

DATE & TIMEVENUESTAFFEVENT
Friday
29-03-2024
15:00 to 17:00
Biomolecular Sciences Building
Seminar Room
Dr Judith Sleeman
Dr Marcus Bischoff
Other O2: Student Video Presentations
2023-4_BL4220_O2

Semester 2: Week 11

DATE & TIMEVENUESTAFFEVENT
Friday
05-04-2024
15:00 to 17:00
Biomolecular Sciences Building
Seminar Room
Dr Judith Sleeman
Dr Marcus Bischoff
Other O3: Student Video Presentations
2023-4_BL4220_O3
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL4220: Assessment

Coursework = 100%*

The following related information applies to all Biology modules:

School of Biology Marking Criteria: See JH booklet info (st-andrews.ac.uk) 
Late submission of continuous assessment work:

All late submissions of coursework that do not require electronic submission should be made via the Biology Teaching Office, Level 2, BMS Building, North Haugh.
Exam details: See School of Biology UG Handbook JH booklet info (st-andrews.ac.uk)  : All Biology exams will be conducted online for 2022-23.
Exam timetable: See Timetables - Exams - University of St Andrews (st-andrews.ac.uk) 
Expected attendance: See JH booklet info (st-andrews.ac.uk)  for detailed attendance requirements.
Good Academic Practice & Avoiding Academic Misconduct: See JH booklet info (st-andrews.ac.uk)
University Student Handbook: University Student Handbook
School and University regulations in the School and University Undergraduate Handbook relating to absence reporting, penalties and rules for late submission of work, extensions for coursework, return of coursework, S-coding, good academic practice and Academic Alerts.: JH booklet info (st-andrews.ac.uk)
University Student Handbook
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

Who to ask

(Information in this section applies to all Biology Modules)

Before contacting staff, students should check the content of the Biology Undergraduate Handbook, the module handbook and specific task instructions.

Questions about Contact
General teaching matters Biology Teaching Office ( bioteach@st-andrews.ac.uk )
Rescheduled or cancelled events Check your University email
Lecture or practical content The lecturer who presented the material
Completing assessed practical assignments The lecturer who set the assignment
Completing assessments Module Organiser (Dr Judith Sleeman jes14@st-andrews.ac.uk)
Marking on continuous assessment The Demonstrator or Module Organiser (Dr Judith Sleeman jes14@st-andrews.ac.uk)
Marking on exams Module Organiser (Dr Judith Sleeman jes14@st-andrews.ac.uk)
Rearranging practical days
Module Organiser (Dr Judith Sleeman jes14@st-andrews.ac.uk)
Absence and/or extensions Module Organiser (Dr Judith Sleeman jes14@st-andrews.ac.uk)

and the Biology Teaching Office ( bioteach@st-andrews.ac.uk )

Difficulties with academic progress which impact more than one module:

Year Coordinator

See School of Biology UG Handbook for list:
JH booklet info (st-andrews.ac.uk)

Overall performance, progress or future directions:

Advisor of Studies

Disability:

Disability Coordinator ( biodisabilities@st-andrews.ac.uk )

For advice and support on any issue e.g. academic, financial, international, personal or health matters, or if you are unsure of who to go to for help:

Advice & Support Centre

Address: 79 North Street, St Andrews

Email: theasc@st-andrews.ac.uk

Web: https://www.standrews.ac.uk/ask-a-question/

Tel: 01334 462020

University assistance with urgent matters out of office hours:

Tel: 01334 476161

Web: https://www.st-andrews.ac.uk/students/advice/counselling/incrisis/

Biology Teaching Office:

We are happy to hear from you about teaching matters. The School of Biology Teaching Office is open Monday to Friday 09.00 - 13.00 and 14.00 - 17.00. School of Biology staff will respond to your emails during these hours. Our team will provide a response to you within three working days.

Biology Teaching Office (Level 2), University of St Andrews, Biomolecular Sciences Building, North Haugh, St Andrews, Fife KY16 9ST

Email: bioteach@st-andrews.ac.uk

Tel: 01334 46 3602 or 3566

BL4220: Contributing Staff

Dr Judith Sleeman
(Module Organiser)

Senior Lecturer in Cell and Developmental Biologyjes14@st-andrews.ac.uk
Dr Marcus BischoffLecturermb273@st-andrews.ac.uk
Dr Gareth MilesReadergbm4@st-andrews.ac.uk
Dr Judith Sleeman
(Module Organiser)
Senior Lecturer in Cell and Developmental Biologyjes14@st-andrews.ac.uk
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL4220: Learning Outcomes

Students completing module BL4220 successfully should be able to:

  • €¢ Understand the aspects of cell biology affected in degenerative conditions
  • €¢ Gain experience of critical evaluation of classic and current primary literature
  • €¢ Gain understanding of personal experiences of degenerative disease
  • €¢ Experience presentation of key scientific concepts to a lay audience
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL4220: Acquired Skills

Practical Skills

    Transferable Skills

    • Conducting interviews
    • Group discussion - leading
    • Group discussion - participating
    • Journal club
    • Short group presentation on given topic (up to 15 min)
    • Paper critique
    • Critically evaluating sources/information
    • Finding information on the web
    • Finding literature
    • Searching databases
    • Sourcing figures/tables
    • Ethical considerations
    • Generating questions
    • Peer assessment
    • Reflective analysis
    • Self assessment
    • Problem-solving questions
    • Data analysis
    • Produce graphs/figures
    • Critiquing experimental design
    • Designing experiments
    • Organising group work
    • Working in pairs/small groups
    Data Sources: information in this online module handbook is gathered from several sources.
    Small footnote marks beside content, or by section titles indicate the source.
    * University of St Andrews Module Catalogue
    School of Biology Symbiosis Database (module organisers only)
    University of St Andrews MMS (St Andrews users only)

    Policies

    (Information in this section applies to all Biology Modules)

    • The procedures and regulations followed by the School of Biology are outlined in the University Handbook and in the School of Biology UG handbook  JH booklet info (st-andrews.ac.uk) 
    • All coursework associated with the module must be completed and submitted by its due date.
    • Specific School regulations relating to absence reporting, penalties and rules for late submission of work, extensions for coursework, return of coursework, S-coding, Good Academic Practice and Academic Alert are stated in the School of Biology UG hand book JH booklet info (st-andrews.ac.uk)  and students are required to carefully read these regulations.
    • Students are also referred to the University Handbook, available at: http://www.st-andrews.ac.uk/studenthandbook/