Biology Online Module Handbook

BL3302 Gene Regulation

(BL3302 online module handbook version 17)

cover image
This module builds on material covered in BL1201 Molecular Biology and BL2104 Biochemistry and Molecular Biology. It first considers the structure of genes and the composition of genomes and then examines genetic activity in eukaryotes in relation to nuclear organisation, chromatin structure and epigenetic mechanisms. Regulation of expression at the levels of gene transcription, RNA processing, RNA stability and translation are next covered in detail, drawing particular attention to the nature of protein-nucleic acid interactions. Specific control mechanisms in different prokaryotic and eukaryotic systems, induced by environmental, cell cycle, and metabolic signals are highlighted.*

Credits: 20*

Semester: 1

Module Organiser
Dr Stuart MacNeill
sam31@st-andrews.ac.uk
01334 467268
Pre-requisite Modules:
BEFORE TAKING THIS MODULE YOU SHOULD PASS BL2302 AND ( PASS BL2306 OR PASS BL2309 )*
Anti-requisite Modules:
None*
Post-requisite Modules:
BL4223, BL5421*
Additional Module Information:
Please check MMS regularly for additional module information


Biology Teaching Office:
Room 1.17, Biomolecular Sciences Building, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST

Email: bioteach@st-andrews.ac.uk      Tel: 01334  463602

BL3302: Timetable

Legend (not all modules have every event type):
lecture
tutorial
workshop
practical
other

Semester 1: Week 1

DATE & TIMEVENUESTAFFEVENT
Tuesday
19-09-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Stuart MacNeill

Lecture L1: Introduction to BL3302
2017-8_BL3302_L1
Wednesday
20-09-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Prof Malcolm White

Lecture L2: Bacterial RNA polymerases
2017-8_BL3302_L2

Semester 1: Week 2

DATE & TIMEVENUESTAFFEVENT
Monday
25-09-2017
10:00 to 11:00
Purdie Building
Lecture Theatre B
Prof Malcolm White

Lecture L3: Bacterial transcription
2017-8_BL3302_L3
Tuesday
26-09-2017
10:00 to 11:00
Purdie Building
Lecture Theatre B
Prof Malcolm White

Lecture L4: Archaeal transcription
2017-8_BL3302_L4
Wednesday
27-09-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Prof Malcolm White

Lecture L5: Riboswitches
2017-8_BL3302_L5

Semester 1: Week 3

DATE & TIMEVENUESTAFFEVENT
Monday
02-10-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Stuart MacNeill

Lecture L6: Eukaryotic RNA polymerase II
2017-8_BL3302_L6
Tuesday
03-10-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Stuart MacNeill

Lecture L7: Eukaryotic transcription initiation
2017-8_BL3302_L7
Wednesday
04-10-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Stuart MacNeill

Lecture L8: Introduction to lab class 1
2017-8_BL3302_L8
Thursday
05-10-2017
09:00 to 17:00
Purdie Building
Purdie Teaching Lab
Dr Stuart MacNeill

Practical P1: Lab class 1
2017-8_BL3302_P1
Friday
06-10-2017
09:00 to 17:00
Purdie Building
Purdie Teaching Lab
Dr Stuart MacNeill

Practical P2: Lab class 1
2017-8_BL3302_P2

Semester 1: Week 4

DATE & TIMEVENUESTAFFEVENT
Monday
09-10-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Stuart MacNeill

Lecture L9: Eukaryotic RNA polymerases I and III
2017-8_BL3302_L9
Tuesday
10-10-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Stuart MacNeill

Workshop W1: Data analysis session
2017-8_BL3302_W1
Wednesday
11-10-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Helder Ferreira

Lecture L10: Chromatin, histone code, etc. 1
2017-8_BL3302_L10

Semester 1: Week 5

DATE & TIMEVENUESTAFFEVENT
Monday
16-10-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Helder Ferreira

Lecture L11: Chromatin, histone code, etc. 2
2017-8_BL3302_L11
Tuesday
17-10-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Stuart MacNeill

Lecture L12: Review writing, referencing and plagiarism
2017-8_BL3302_L12
Wednesday
18-10-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Stuart MacNeill

Lecture L13: Introduction to lab class 2
2017-8_BL3302_L13
Thursday
19-10-2017
09:00 to 17:00
Purdie Building
Purdie Teaching Lab
Dr Stuart MacNeill

Practical P3: Lab class 2
2017-8_BL3302_P3
Friday
20-10-2017
09:00 to 17:00
Purdie Building
Purdie Teaching Lab
Dr Stuart MacNeill

Practical P4: Lab class 2
2017-8_BL3302_P4

Semester 1: Week 7

DATE & TIMEVENUESTAFFEVENT
Monday
30-10-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Helder Ferreira

Lecture L14: Chromatin, histone code, etc. 3
2017-8_BL3302_L14
Tuesday
31-10-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Helder Ferreira

Lecture L15: Chromatin, histone code, etc. 4
2017-8_BL3302_L15
Wednesday
01-11-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Katerina Zabrady

Workshop W2: Data analysis session
2017-8_BL3302_W2

Semester 1: Week 8

DATE & TIMEVENUESTAFFEVENT
Monday
06-11-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Judith Sleeman

Lecture L16: RNA processing and nuclear dynamics
2017-8_BL3302_L16
Tuesday
07-11-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Judith Sleeman

Lecture L17: RNA processing and nuclear dynamics
2017-8_BL3302_L17
Wednesday
08-11-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Judith Sleeman

Lecture L18: RNA processing and nuclear dynamics
2017-8_BL3302_L18

Semester 1: Week 9

DATE & TIMEVENUESTAFFEVENT
Monday
13-11-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Judith Sleeman

Lecture L19: RNA processing and nuclear dynamics
2017-8_BL3302_L19
Tuesday
14-11-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Judith Sleeman

Workshop W3: Data analysis session
2017-8_BL3302_W3
Wednesday
15-11-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Prof Martin Ryan

Lecture L20: Translation 1
2017-8_BL3302_L20

Semester 1: Week 10

DATE & TIMEVENUESTAFFEVENT
Monday
20-11-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Prof Martin Ryan

Lecture L21: Translation 2
2017-8_BL3302_L21
Tuesday
21-11-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Stuart MacNeill

Lecture L22: Introduction to lab class 3
2017-8_BL3302_L22
Wednesday
22-11-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Prof Martin Ryan

Lecture L23: Translation 3
2017-8_BL3302_L23
Thursday
23-11-2017
09:00 to 17:00
Purdie Building
Purdie Teaching Lab
Dr Stuart MacNeill

Practical P5: Lab class 3
2017-8_BL3302_P5
Friday
24-11-2017
09:00 to 17:00
Purdie Building
Purdie Teaching Lab
Dr Stuart MacNeill

Practical P6: Lab class 3
2017-8_BL3302_P6

Semester 1: Week 11

DATE & TIMEVENUESTAFFEVENT
Monday
27-11-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Prof Martin Ryan

Lecture L24: Translation 4
2017-8_BL3302_L24
Tuesday
28-11-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Prof Martin Ryan

Workshop W4: Data analysis session
2017-8_BL3302_W4
Wednesday
29-11-2017
10:00 to 11:00
Biomolecular Sciences Building
BMS Lecture Theatre
Dr Stuart MacNeill

Lecture L25: Module summary
2017-8_BL3302_L25
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL3302: Reading List

Click for BL3302 reading list

BL3302: Assessment

3-hour Written Examination = 66%, Coursework = 34%*

Assessment:
Review article
Due by:
17/11/2017 16:00
Feedback due by:
08/12/2017 16:00
Type:
Single Upload
Weight:
1%
Assessment:
Lab report
Due by:
01/12/2017 16:00
Feedback due by:
22/12/2017 16:00
Type:
Single Upload
Weight:
1%

(MMS assessment data cached: 22 October 2017 22:20:09.)


The following related information applies to all Biology modules:

School of Biology Marking Criteria: See School of Biology Undergraduate Handbook
Late submission of continuous assessment work:

All late submissions of coursework that do not require electronic submission should be made via the late submissions box in the Biomolecular Science Building (beside the Teaching Office)
Exam details: See School of Biology Undergraduate Handbook
Exam timetable: see http://www.st-andrews.ac.uk/students/academic/examinations/examtimetablescurrent/
Expected attendance: See School of Biology Undergraduate Handbook for detailed attendance requirements.
Good Academic Practice & Avoiding Academic Misconduct: See School of Biology Undergraduate Handbook
University Student Handbook: University Student Handbook
School and University regulations in the School and University Undergraduate Handbook relating to absence reporting, penalties and rules for late submission of work, extensions for coursework, return of coursework, S-coding, good academic practice and Academic Alerts.: School of Biology Undergraduate Handbook University Student Handbook
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

Who to ask

(Information in this section applies to all Biology Modules)

Questions about different aspects of the module should be directed to different people:

Questions about Contact
General teaching matters Biology Teaching Office ( bioteach@st-andrews.ac.uk )
Rescheduled or cancelled events Check your University email
Lecture or practical content The lecturer who presented the material
Completing assessed practical assignments The lecturer who set the assignment
Completing assessments Module Organiser (Dr Stuart MacNeill sam31@st-andrews.ac.uk)
Marking on continuous assessment The Demonstrator or Module Organiser (Dr Stuart MacNeill sam31@st-andrews.ac.uk)
Marking on exams Module Organiser (Dr Stuart MacNeill sam31@st-andrews.ac.uk)
Rearranging practical days Grant Brown
Absence and/or extensions Module Organiser (Dr Stuart MacNeill sam31@st-andrews.ac.uk) and the Biology Teaching Office ( bioteach@st-andrews.ac.uk )

Difficulties with academic progress which impact more than one module:

Year Coordinator

See School of Biology Undergraduate student handbook for list: http://biology.st-andrews.ac.uk/documents/UndergraduateHandbook.pdf

Overall performance, progress or future directions:

Advisor of Studies

Disability:

Disability Coordinator (Dr Jacqueline Nairn jn37@st-andrews.ac.uk)

Biology Teaching Office:

Room 1.17, Biomolecular Sciences Building, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST

Email: bioteach@st-andrews.ac.uk

Tel: 01334 463602

BL3302: Contributing Staff

Dr Stuart MacNeill

Dr Stuart MacNeill
(Module Organiser)

SULSA Reader in Translational Biologysam31@st-andrews.ac.uk
Dr Helder FerreiraDr Helder FerreiraLecturerhcf2@st-andrews.ac.uk
Dr Stuart MacNeillDr Stuart MacNeill
(Module Organiser)
SULSA Reader in Translational Biologysam31@st-andrews.ac.uk
Prof Martin RyanProf Martin RyanProfessor of Translational Virologymdr1@st-andrews.ac.uk
Dr Judith SleemanDr Judith SleemanLecturer in Cell and Developmental Biologyjes14@st-andrews.ac.uk
Prof Malcolm WhiteProf Malcolm WhiteProfessormfw2@st-andrews.ac.uk
Dr Katerina ZabradyResearch Fellowzk22@st-andrews.ac.uk
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL3302: Learning Outcomes

Students completing module BL3302 successfully should be able to:

  • have a good knowledge and understanding of the topics outlined in this module
  • be able to apply this knowledge and understanding to the specific areas of study in other modules
  • be able to read research papers and listen to research talks with a better understanding
  • be able to express clearly the content of research papers
  • record experimental results and interpret data as well as report findings and conclusions in a precise and clear manner
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL3302: Acquired Skills

Practical Skills

  • Agarose gel
  • DNA isolation
  • Handling microbes
  • Pipetting
  • Polymerase Chain Reaction (PCR)
  • Protein purification
  • Restriction digest
  • SDS PAGE
  • Western Blot

Transferable Skills

  • Review article on given topic
  • Lab safety awareness
  • Concentrations
  • Dilutions
  • Lab or field notebook
  • Designing experiments
  • Working in pairs/small groups
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

Policies

(Information in this section applies to all Biology Modules)