Profile

Dr Ildiko Somorjai:
MASTS Lecturer



My research interests are broadly in evolution and development, with a focus on comparative mechanisms between embryonic processes and regeneration. The main body of my work is carried out in the cephalochordate amphioxus, an invertebrate chordate that is fast emerging as an important model system for understanding the evolution of vertebate characters from an invertebrate ancestor. This is largely facilitated by its "prototypical" genome organisation and simple chordate morphology. The fact that amphioxus regenerates complex structures well as an adult also holds promise for its use as a regeneration model system.

 



Ildiko is a newly appointed MASTS Lecturer. Her interests are in the field of evolution and development (“Evo-Devo”), including the evolution of regeneration mechanisms and stem cells . She employs a comparative framework to study the amazing diversity of regenerative ability in different systems, particularly marine organisms . The long-term goal of her research is to shed light on new facets of the regulation of stem cells in species with high regenerative potential, in an effort to improve organ regeneration in poorly regenerating species, like humans.

source: symbiosis


Recent Publications:

Recent publications listed in research@st-andrews
Albuixech-Crespo, B, López-Blanch, L, Burguera, D, Maeso, I, Sánchez Arrones, L, Moreno-Bravo, JA, Somorjai, I, Pascual-Anaya, J, Puelles, E, Bovolenta, P, Garcia-Fernàndez, J, Puelles, L, Irimia, M & Ferran, JL 2017, 'Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain' PLoS Biology, vol 15, no. 4, e2001573. DOI: 10.1371/journal.pbio.2001573
Bertrand, S, Aldea, D, Oulion, S, Subirana, L, de Lera, AR, Somorjai, IML & Escriva, H 2015, 'Evolution of the role of RA and FGF signals in the control of somitogenesis in chordates' PLoS One, vol 10, no. 9, e0136587. DOI: 10.1371/journal.pone.0136587
Pascual Anaya, J, Albuixech Crespo, B, Somorjai, IML, Carmona, R, Oisi, Y, Àlvarez, S, Kuratani, S, Muñoz Chápuli, R & Garcia Fernandez, J 2013, 'The evolutionary origins of chordate hematopoeisis and vertebrate endothelia' Developmental Biology. DOI: 10.1016/j.ydbio.2012.11.015
Somorjai, IML, Lohmann, JU, Holstein, TW & Zhao, Z 2012, 'Stem cells: A view from the roots' Biotechnology Journal, vol 7, no. 6, pp. 704-722. DOI: 10.1002/biot.201100349