Dr Catherine Botting:

Dr Catherine Botting

Dr Catherine Botting
Biomolecular Sciences Building
University of St Andrews
North Haugh
St Andrews
KY16 9ST

tel: 01334 467302
fax: 01334 462595
room: B114

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School of Chemistry Profile

School of Biology
School of Chemistry
Biomedical Sciences Research Complex

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Mass spectrometry can be used to study a wide range of biological problems.  We use both MALDI and ESI ionization techniques and apply them to a broad spectrum of sample types. However, the main focus of our work is on using proteomics-type analysis techniques to identify the proteins present in a sample. This can range from relatively routine analysis of simple samples, through to the quantitative analysis of complex mixtures of proteins, looking for those proteins whose expression levels have been altered by the experimental conditions.  Another important area of our work is in mapping sites of modification by interpretation of peptide fragmentation patterns. We collaborate with researchers both internal and external to St Andrews, working closely with them to use our methods to answer their scientific questions.


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Recent Publications:

5 (of 101 published available) for cb2 (source: University of St Andrews PURE)
Please click title of any item for full details

Insights into the mechanism of the cyanobactin heterocyclase enzyme Clarissa Melo Czekster, Catherine Helen Botting, Uli Schwarz-Linek, Jim Naismith
Biochemistry 2019 vol.58 pp.2125-2132
Quantitative proteomic changes in LPS-activated monocyte-derived dendritic cells Swati Arya, Silvia Anna Synowsky, Sally Lorna Shirran, Catherine Helen Botting, Simon John Powis, Alan J. Stewart
Scientific Reports 2019 vol.9
Identification of synovial fluid proteins that are associated with early osteoarthritis treatment failure C. H. Hulme, H. R. Fuller, S. Roberts, J. B. Richardson, P. Gallacher, M. J. Peffers, Sally Lorna Shirran, Catherine Helen Botting, K. T. Wright
International journal of experimental pathology 2018 vol.99 pp.A2-A2
Linking microbial community structure and function during the acidified anaerobic digestion of grass Aoife Joyce, Umer Z. Ijaz, Corine Nzeteu, Aoife Vaughan, Sally Lorna Shirran, Catherine Helen Botting, Christopher Quince, Vincent O’Flaherty, Florence Abram
Frontiers in Microbiology 2018 vol.9
Neurochondrin interacts with the SMN protein suggesting a novel mechanism for Spinal Muscular Atrophy pathology Kim D. Morrison, Sally Lorna Shirran, Ewout J. N. Groen, Tom H. Gillingwater, Catherine Helen Botting, Judith Elizabeth Sleeman
Journal of Cell Science 2018 vol.131