Profile

Dr Catherine Botting:
Lecturer

Dr Catherine Botting

Dr Catherine Botting
Biomolecular Sciences Building
University of St Andrews
North Haugh
St Andrews
KY16 9ST
Fife
UK

tel: 01334 467302
fax: 01334 462595
room: B114
email: cb2@st-andrews.ac.uk

Related Content:

research@st-andrews
School of Chemistry Profile

School of Biology
School of Chemistry
Biomedical Sciences Research Complex

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Mass spectrometry can be used to study a wide range of biological problems.  We use both MALDI and ESI ionization techniques and apply them to a broad spectrum of sample types. However, the main focus of our work is on using proteomics-type analysis techniques to identify the proteins present in a sample. This can range from relatively routine analysis of simple samples, through to the quantitative analysis of complex mixtures of proteins, looking for those proteins whose expression levels have been altered by the experimental conditions.  Another important area of our work is in mapping sites of modification by interpretation of peptide fragmentation patterns. We collaborate with researchers both internal and external to St Andrews, working closely with them to use our methods to answer their scientific questions.

 



source: symbiosis


Recent Publications:

Recent publications listed in research@st-andrews
Ashton, NW, Paquet, N, Shirran, SL, Bolderson, E, Kariawasam, R, Touma, C, Fallahbaghery, A, Gamsjaeger, R, Cubeddu, L, Botting, C, Pollock, PM, O’Byrne, KJ & Richard, DJ 2017, 'hSSB1 phosphorylation is dynamically regulated by DNA-PK and PPP-family protein phosphatases' DNA Repair, vol In press. DOI: 10.1016/j.dnarep.2017.03.006