Dr Catherine Botting:

Dr Catherine Botting

Dr Catherine Botting
Biomolecular Sciences Building
University of St Andrews
North Haugh
St Andrews
KY16 9ST

tel: 01334 467302
fax: 01334 462595
room: B114

Related Content:

School of Chemistry Profile

School of Biology
School of Chemistry
Biomedical Sciences Research Complex

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Mass spectrometry can be used to study a wide range of biological problems.  We use both MALDI and ESI ionization techniques and apply them to a broad spectrum of sample types. However, the main focus of our work is on using proteomics-type analysis techniques to identify the proteins present in a sample. This can range from relatively routine analysis of simple samples, through to the quantitative analysis of complex mixtures of proteins, looking for those proteins whose expression levels have been altered by the experimental conditions.  Another important area of our work is in mapping sites of modification by interpretation of peptide fragmentation patterns. We collaborate with researchers both internal and external to St Andrews, working closely with them to use our methods to answer their scientific questions.


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Recent Publications:

Recent publications

5  (of 99 published available) for cb2. (source: University of St Andrews PURE)
Please click title of any item for full details.

2019 (13/3)
Scientific Reports
Quantitative proteomic changes in LPS-activated monocyte-derived dendritic cells
Swati Arya, Silvia Anna Synowsky, Sally Lorna Shirran, Catherine Helen Botting, Simon John Powis, Alan J. Stewart 
2018 (21/3)
Frontiers in Microbiology
Linking microbial community structure and function during the acidified anaerobic digestion of grass
Aoife Joyce, Umer Z. Ijaz, Corine Nzeteu, Aoife Vaughan, Sally Lorna Shirran, Catherine Helen Botting, Christopher Quince, Vincent O’Flaherty, Florence Abram 
Keywords: Anaerobic digestion, Cellulosic substrate, 16S rRNA profiling, Metaproteomics, Biomolecule co-extraction
2018 (17/4)
Journal of Cell Science
Neurochondrin interacts with the SMN protein suggesting a novel mechanism for Spinal Muscular Atrophy pathology
Kim D. Morrison, Sally Lorna Shirran, Ewout J. N. Groen, Tom H. Gillingwater, Catherine Helen Botting, Judith Elizabeth Sleeman 
Keywords: Spinal Muscular Atrophy, Neurochondrin, SMN, Sm proteins, snRNPs
Conservation Physiology
Not just fat
Joanna Louise Kershaw, Catherine Helen Botting, Andrew Brownlow, Ailsa Jane Hall 
Keywords: Adipose tissue, Biomarkers, Marine mammals, Metabolism, Proteomics
2018 (7)
Experimental Eye Research
vol.172 pp.21-29
Quantitative analysis of hydroxyapatite-binding plasma proteins in genotyped individuals with late-stage age-related macular degeneration
Swati Arya, Eszter Emri, Silvia Anna Synowsky, Sally Lorna Shirran, Neda Barzegar-Befroei, Tunde Peto, Catherine Helen Botting, Imre Lengyel, Alan J. Stewart 
Keywords: Drusen, Sub-retinal pigment epithelial deposits, Mineral-protein interactions, Retinal disease, Quantitative proteomics