CENTRE

OF

BIOPHOTONICS

 Light-based innovation for the biosciences

My research is interdisciplinary and sits at the interface between the basic sciences and medicine. Research in my laboratory is focused upon how metal ions are handled in the body and the roles they play in regulating medically/physiologically relevant processes such as insulin signalling and coagulation. Collectively, my work provides detailed and reliable data relating to the transport and speciation of metal ions (particularly zinc) in the circulation and new insights into their cellular functions and role in disease states. Currently my team are examining ways in which defective metal handling contributes to pathogenesis of vascular diseases, including thrombosis and vascular eye disease.

Research areas:

  • albumin
  • haemostasis
  • metals
  • proteomics

Metal handling in blood plasma – Alan Stewart’s group