Light-based innovation for the biosciences

Judith Sleeman studied for a BSc in Cellular and Molecular Pathology at the University of Bristol, followed by a PhD in Stem Cell Biology at the University of Edinburgh. Following several years as a postdoc in Angus Lamond’s group at the University of Dundee, she was awarded a Royal Society University Research Fellowship to study the physical organisation of RNA processing in mammalian cells and the impact of this on human disease. Moving to the University of St Andrews School of Biology in 2007, Judith is now a senior lecturer and a member of the Motor Neuron Disease Scotland Research Committee.

Leading on from early work into the cellular organisation of splicing snRNP maturation, research in the Sleeman lab has expanded to include cytoplasmic transport of mRNA and the effects on cellular structure of triplet repeat disorders. Key techniques include live-cell and high-resolution microscopy and proteomics.

Research areas:

  • Motor neuron disease
  • Myotonic dystrophy
  • RNA processing
  • Cell nucleus
  • Phase transitions

Judith Sleeman research group