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Dr Samantha Pitt is a Senior Lecturer in the School of Medicine and the Divisional Head of Cellular Medicine. Her research focuses on intracellular calcium dynamics in the heart. In individuals with heart failure and fatal arrhythmias the release of calcium becomes erratic leading to weakened contraction of heart muscle and cell death. Using a combination of low noise electrophysiological recordings, live cell imaging, molecular and biochemical methods, her group investigates the cellular mechanisms that underlie cardiac dysfunction, with a focus on intracellular calcium release channels. Her research challenges current understanding of cardiac function with a focus to uncover new drug targets in the treatment of the failing heart

Research areas:

  • Ion chanels
  • Calcium signalling
  • Cardiovascular research
  • Electrophysiology
  • Pharmacology

Samantha Pitt research group