BL4223 Molecular and cell biology of eukaryotic DNA replication
(BL4223 online module handbook version 39)
Highly-efficiently chromosomal DNA replication is essential for all forms of cellular life on Earth and requires the complex interplay of a large range of protein factors in a temporally- and spatially-coordinated manner. In humans, defects in the replication process may lead to genetic disease or cancer. This module will summarise current knowledge of the enzymes and mechanisms of chromosomal DNA replication in bacterial, archaeal and eukaryotic cells with particular emphasis on exploring the diverse range of experimental systems and techniques used in the laboratory to probe the structure, function and regulation of the replication apparatus. Similarities and differences between cellular and viral DNA replication strategies will be explored and diverse aspects of the evolution of the replication machinery highlighted.
*Credits: 15*
Semester: 1†
Module OrganiserPre-requisite Modules:Before taking this module you must pass BL3301 and pass BL3302*
Anti-requisite Modules:*
Post-requisite Modules:*
Additional Module Information:
Biology Teaching Office:
Level 2, Biomolecular Sciences Building, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST
Email: bioteach@st-andrews.ac.uk Phone: +44 (0)1334 46 3602 or 3566
BL4223: Assessment
1.5-hour Written Examination = 40%, Coursework = 60%*
The following related information applies to all Biology modules:
Who to ask †
(Information in this section applies to all Biology Modules)
Before contacting staff, students should check the content of the Biology Undergraduate Handbook, the module handbook and specific task instructions.
Biology Teaching Office:
We are happy to hear from you about teaching matters. The School of Biology Teaching Office is open Monday to Friday 09.00 - 13.00 and 14.00 - 17.00. School of Biology staff will respond to your emails during these hours. Our team will provide a response to you within three working days.
Biology Teaching Office (Level 2), University of St Andrews, Biomolecular Sciences Building, North Haugh, St Andrews, Fife KY16 9ST
Email: bioteach@st-andrews.ac.uk
Tel: 01334 46 3602 or 3566
BL4223: Contributing Staff †
BL4223: Learning Outcomes †
No details are currently available for Learning Outcomes
†BL4223: Acquired Skills †
Practical Skills
Transferable Skills
- Group discussion - participating
- Long individual presentation on given topic (>15 min)
- Short individual presentation on given topic (up to 15 min)
- Summary
- Critically evaluating sources/information
Policies †
(Information in this section applies to all Biology Modules)
- The procedures and regulations followed by the School of Biology are outlined in the University Handbook and in the School of Biology UG handbook  JH booklet info (st-andrews.ac.uk)Â
- All coursework associated with the module must be completed and submitted by its due date.
- Specific School regulations relating to absence reporting, penalties and rules for late submission of work, extensions for coursework, return of coursework, S-coding, Good Academic Practice and Academic Alert are stated in the School of Biology UG hand book JH booklet info (st-andrews.ac.uk)  and students are required to carefully read these regulations.
- Students are also referred to the University Handbook, available at: http://www.st-andrews.ac.uk/studenthandbook/