Biology Online Module Handbook

BL4213 Molecular Virology

(BL4213 online module handbook version 26)

cover image
Viruses as a group include many important human and veterinary pathogens such as influenza virus, hepatitis C virus, foot and mouth disease virus as well as emerging viruses like Ebola virus, and remain a continuing threat to human and animal welfare. This module will consist of a mixture of lectures, tutorials and personal-based learning on aspects of RNA virus host interactions. The topics covered will include comparison of the molecular mechanisms employed by enveloped and non-enveloped viruses to enter and exit from cells, discussion of how small RNA viruses maximise their coding capacity, comparison of the replication of positive and negative strand RNA viruses, discussion of how selected viruses reprogram the host cell to ensure their own replication, description of how RNA viruses intercede with innate immune responses, and understanding of how selected viruses interact with their vectors. In addition, discussion of virus-related topics that have made headline news in recent years will be addressed, and an understanding of the more commonly used molecular techniques to study viruses will be expected.*

Credits: 15*

Semester: 1

Module Organiser
Prof Richard Randall
rer@st-andrews.ac.uk
01334 463397
Pre-requisite Modules:
BEFORE TAKING THIS MODULE YOU SHOULD PASS BL3311*
Anti-requisite Modules:
None*
Post-requisite Modules:
*
Additional Module Information:
Please check MMS regularly for additional module information


Biology Teaching Office:
Room 1.17, Biomolecular Sciences Building, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST

Email: bioteach@st-andrews.ac.uk      Tel: 01334  463602

BL4213: Timetable

Legend (not all modules have every event type):
lecture
tutorial
workshop
practical
other

Semester 1: Week 1

DATE & TIMEVENUESTAFFEVENT
Wednesday
20-09-2017
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Prof Richard Randall

Lecture L1: Introduction to the elective
2017-8_BL4213_L1
Friday
22-09-2017
11:00 to 12:00
Biomolecular Sciences Building
Lecture Theatre
Prof Martin Ryan

Lecture L2: Virus replication: manipulation of host cells I
2017-8_BL4213_L2

Semester 1: Week 2

DATE & TIMEVENUESTAFFEVENT
Wednesday
27-09-2017
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Prof Martin Ryan

Lecture L3: Virus replication: manipulation of host cells II
2017-8_BL4213_L3
Friday
29-09-2017
11:00 to 12:00
Biomolecular Sciences Building
Lecture Theatre
Dr Michael M Nevels

Lecture L4: Human tumour viruses
2017-8_BL4213_L4

Semester 1: Week 3

DATE & TIMEVENUESTAFFEVENT
Wednesday
04-10-2017
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Michael M Nevels

Lecture L5: Viral oncogenic mechanisms
2017-8_BL4213_L5
Friday
06-10-2017
11:00 to 12:00
Biomolecular Sciences Building
Lecture Theatre
Prof Richard Randall

Lecture L6: Innate immunity to viruses in mammals I
2017-8_BL4213_L6

Semester 1: Week 4

DATE & TIMEVENUESTAFFEVENT
Wednesday
11-10-2017
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Prof Richard Randall

Lecture L7: Innate immunity to viruses in mammals II
2017-8_BL4213_L7
Friday
13-10-2017
11:00 to 12:00
Biomolecular Sciences Building
Dr Jens Tilsner

Lecture L8: Innate immunity to viruses in plants
2017-8_BL4213_L8

Semester 1: Week 5

DATE & TIMEVENUESTAFFEVENT
Wednesday
18-10-2017
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Prof David Evans

Lecture L9: Emerging viruses - mechanisms and examples I
2017-8_BL4213_L9
Friday
20-10-2017
11:00 to 12:00
Biomolecular Sciences Building
Lecture Theatre
Prof David Evans

Lecture L10: Emerging viruses - mechanisms and examples II
2017-8_BL4213_L10

Semester 1: Week 7

DATE & TIMEVENUESTAFFEVENT
Wednesday
01-11-2017
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Prof David Evans

Lecture L11: Emerging viruses - mechanisms and examples III
2017-8_BL4213_L11
Friday
03-11-2017
11:00 to 12:00
Purdie Building
Lecture Theatre C
Prof David Evans

Lecture L12: Interpretation of research papers
2017-8_BL4213_L12

Semester 1: Week 8

DATE & TIMEVENUESTAFFEVENT
Wednesday
08-11-2017
12:00 to 13:00
Biomedical Sciences Building
Lecture Theatre
Dr Catherine Adamson

Lecture L13: Human Immunodeficency Virus
2017-8_BL4213_L13
Friday
10-11-2017
14:00 to 17:00
Biomedical Sciences Building
Lecuture Theatre
Prof David Evans

Lecture L14: Interpretation of Research Paper Assignment
2017-8_BL4213_L14

Semester 1: Week 12

DATE & TIMEVENUESTAFFEVENT
Wednesday
06-12-2017
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Prof Richard Randall

Lecture L15: Question and answers (review of course)
2017-8_BL4213_L15
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL4213: Reading List

Click for BL4213 reading list

BL4213: Assessment

3-hour Written Examination = 60%, Coursework = 40%*

Assessment:
Interpretation of research paper
Due by:
04/10/2017 23:59
Feedback due by:
25/10/2017 23:59
Type:
Paper Hand-in
Weight:
75%
Assessment:
viruses in the news
Due by:
10/11/2017 23:59
Feedback due by:
01/12/2017 23:59
Type:
Paper Hand-in
Weight:
25%

(MMS assessment data cached: 20 September 2017 22:20:10.)


The following related information applies to all Biology modules:

School of Biology Marking Criteria: See School of Biology Undergraduate Handbook
Late submission of continuous assessment work:

All late submissions of coursework that do not require electronic submission should be made via the late submissions box in the Biomolecular Science Building (beside the Teaching Office)
Exam details: See School of Biology Undergraduate Handbook
Exam timetable: see http://www.st-andrews.ac.uk/students/academic/examinations/examtimetablescurrent/
Expected attendance: See School of Biology Undergraduate Handbook for detailed attendance requirements.
Good Academic Practice & Avoiding Academic Misconduct: See School of Biology Undergraduate Handbook
University Student Handbook: University Student Handbook
School and University regulations in the School and University Undergraduate Handbook relating to absence reporting, penalties and rules for late submission of work, extensions for coursework, return of coursework, S-coding, good academic practice and Academic Alerts.: School of Biology Undergraduate Handbook University Student Handbook
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

Who to ask

(Information in this section applies to all Biology Modules)

Questions about different aspects of the module should be directed to different people:

Questions about Contact
General teaching matters Biology Teaching Office ( bioteach@st-andrews.ac.uk )
Rescheduled or cancelled events Check your University email
Lecture or practical content The lecturer who presented the material
Completing assessed practical assignments The lecturer who set the assignment
Completing assessments Module Organiser (Prof Richard Randall rer@st-andrews.ac.uk)
Marking on continuous assessment The Demonstrator or Module Organiser (Prof Richard Randall rer@st-andrews.ac.uk)
Marking on exams Module Organiser (Prof Richard Randall rer@st-andrews.ac.uk)
Rearranging practical days Grant Brown
Absence and/or extensions Module Organiser (Prof Richard Randall rer@st-andrews.ac.uk) and the Biology Teaching Office ( bioteach@st-andrews.ac.uk )

Difficulties with academic progress which impact more than one module:

Year Coordinator

See School of Biology Undergraduate student handbook for list: http://biology.st-andrews.ac.uk/documents/UndergraduateHandbook.pdf

Overall performance, progress or future directions:

Advisor of Studies

Disability:

Disability Coordinator (Dr Jacqueline Nairn jn37@st-andrews.ac.uk)

Biology Teaching Office:

Room 1.17, Biomolecular Sciences Building, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST

Email: bioteach@st-andrews.ac.uk

Tel: 01334 463602

BL4213: Contributing Staff

Prof Richard Randall

Prof Richard Randall
(Module Organiser)

Professor of Molecular Virologyrer@st-andrews.ac.uk
Dr Catherine AdamsonDr Catherine AdamsonLecturer in Molecular Medicinecsa21@st-andrews.ac.uk
Prof David EvansProf David EvansProfessordje2@st-andrews.ac.uk
Dr Michael M NevelsDr Michael M NevelsReader in Virologymmn3@st-andrews.ac.uk
Prof Richard RandallProf Richard Randall
(Module Organiser)
Professor of Molecular Virologyrer@st-andrews.ac.uk
Prof Martin RyanProf Martin RyanProfessor of Translational Virologymdr1@st-andrews.ac.uk
Dr Jens TilsnerDr Jens TilsnerLecturerjt58@st-andrews.ac.uk
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL4213: Learning Outcomes


Students completing module BL4213 successfully should be able to:

  • i. Appreciate that viruses reprogramme cells in order to promote virus replication and that different viruses reprogramme cells in different ways that affects disease outcomes.
  • ii. Recognize the importance of viruses as underlying causes of specific cancers and understand, at the molecular level, how viruses can cause cancer.
  • iii. Realize that viruses counteract innate cellular defence mechanisms in different ways and that the way they do so affects disease outcomes.
  • iv. Understand the factors that lead to the emergence and re-emergence of viruses and why such viruses remain a continual threat to human health and well-being.
  • v. Be generally aware of current concerns about viruses and why they are in the news.
  • vi. Be better able to read and interpret research articles.
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL4213: Acquired Skills

Practical Skills

    Transferable Skills

    • Group discussion - leading
    • Group discussion - participating
    • Completing a research paper from which sections have been removed
    • Opinion piece
    Data Sources: information in this online module handbook is gathered from several sources.
    Small footnote marks beside content, or by section titles indicate the source.
    * University of St Andrews Module Catalogue
    School of Biology Symbiosis Database (module organisers only)
    University of St Andrews MMS (St Andrews users only)

    Policies

    (Information in this section applies to all Biology Modules)