Biology Online Module Handbook

BL3310 Bioenergetics

(BL3310 online module handbook version 34)

cover image

image: Bovine F1-ATPase inhibited by DCCD (dicyclohexylcarbodiimide) (pdb 1E79)

The conversion of one form of energy into another by a biochemical process is at the centre of all life. This module studies the biological systems for conserving energy from food oxidation and light absorption (photosynthesis) and the conversion of the resulting redox energy into chemical energy in the pyrophosphate bonds of ATP. The module also considers electron transfer processes in biology and the energetics of trasport processes. Chemiosmotic theory and the principles are considered in detail as are the structure and function of electron and proton transfer systems of energy tranducing systems. Practical classes will introduce the student to the methods used in this field of study. The module will comprise twenty lectures, eight hours tutorials/seminars in total, and twelve hours in practical classes.*

Credits: 20*

Semester: 2

Module Organiser
Dr Jacqueline Nairn
jn37@st-andrews.ac.uk
01334 463604
Pre-requisite Modules:
BEFORE TAKING THIS MODULE YOU MUST PASS BL2302 OR PASS BL2306*
Anti-requisite Modules:
None*
Post-requisite Modules:
BL4222*
Additional Module Information:
Please check MMS regularly for additional module information


Biology Teaching Office:
The Biology Hive, New Technology Centre, University of St Andrews, North Haugh, St Andrews, Fife KY16 9SR

Email: bioteach@st-andrews.ac.uk      Tel: 01334  463602

BL3310: Timetable

Legend (not all modules have every event type):
lecture
tutorial
workshop
practical
other

Semester 2: Week 1

DATE & TIMEVENUESTAFFEVENT
Monday
29-01-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Jacqueline Nairn

Lecture L1: Introduction
2017-8_BL3310_L1
Tuesday
30-01-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Jacqueline Nairn

Lecture L2: Quantitative bioenergetics
2017-8_BL3310_L2
Wednesday
31-01-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Rona Ramsay

Lecture L3: Electron transfer chain overview
2017-8_BL3310_L3

Semester 2: Week 2

DATE & TIMEVENUESTAFFEVENT
Monday
05-02-2018
09:00 to 17:00
Other
Dr Gerald Prescott

Other O1: JH Careers Event
2017-8_BL3310_O1
Tuesday
06-02-2018
12:00 to 13:00
St Mary's College
Room 3
Dr Rona Ramsay

Lecture L4: Mitochondrial electron transfer chains - Complex I & II
2017-8_BL3310_L4
Wednesday
07-02-2018
12:00 to 13:00
St Mary's College
Room 3
Dr Rona Ramsay

Lecture L5: Mitochondrial electron transfer chains - Complex III
2017-8_BL3310_L5

Semester 2: Week 3

DATE & TIMEVENUESTAFFEVENT
Monday
12-02-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Rona Ramsay

Lecture L6: Mitochondrial electron transfer chains - Complex IV
2017-8_BL3310_L6
Tuesday
13-02-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Rona Ramsay

Lecture L7: ROS
2017-8_BL3310_L7
Wednesday
14-02-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Rona Ramsay

Lecture L8: Introduction to Lab 1
2017-8_BL3310_L8
Thursday
15-02-2018
09:00 to 17:00
Chemistry
Purdie Lab
Dr Rona Ramsay

Practical P1: Characterisation of isolated mitochondria
2017-8_BL3310_P1
Both groups attend both Thu and Fri
Friday
16-02-2018
09:00 to 17:00
Chemistry
Purdie Lab
Dr Rona Ramsay

Practical P2: Characterisation of isolated mitochondria
2017-8_BL3310_P2
Both groups attend both Thu and Fri

Semester 2: Week 4

DATE & TIMEVENUESTAFFEVENT
Monday
19-02-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Rona Ramsay

Tutorial T1: Practical review & data handling
2017-8_BL3310_T1
Tuesday
20-02-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Jacqueline Nairn

Lecture L9: Bacterial Systems
2017-8_BL3310_L9
Wednesday
21-02-2018
12:00 to 13:00
Biomedical Sciences Building
Lecture Theatre
Prof Peter Heathcote

Lecture L10: Photosynthesis I
2017-8_BL3310_L10

Semester 2: Week 5

DATE & TIMEVENUESTAFFEVENT
Monday
26-02-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Prof Peter Heathcote

Lecture L11: Photosynthesis II
2017-8_BL3310_L11
Tuesday
27-02-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Prof Peter Heathcote

Lecture L12: Photosynthesis III
2017-8_BL3310_L12
Wednesday
28-02-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Prof Peter Heathcote

Lecture L13: Photosynthesis IV
2017-8_BL3310_L13

Semester 2: Week 6

DATE & TIMEVENUESTAFFEVENT
Monday
05-03-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Jacqueline Nairn

Lecture L14: ATPase I
2017-8_BL3310_L14
Tuesday
06-03-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Jacqueline Nairn

Lecture L15: ATPase II
2017-8_BL3310_L15
Wednesday
07-03-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Jacqueline Nairn

Lecture L16: Mitochondrial biogenesis
2017-8_BL3310_L16

Semester 2: Week 7

DATE & TIMEVENUESTAFFEVENT
Monday
12-03-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Rafael Guimaraes da Silva

Lecture L17: Mitochondiria & Microscopy
2017-8_BL3310_L17
Tuesday
13-03-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Gerald Prescott

Lecture L18: Signalling between mitochondria and the cell
2017-8_BL3310_L18
Wednesday
14-03-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Jacqueline Nairn

Lecture L19: Introduction to Lab 2
2017-8_BL3310_L19
Thursday
15-03-2018
10:00 to 17:00
Chemistry
Purdie Lab
Dr Jacqueline Nairn

Practical P3: Characterisation of mitochondrial complexes
2017-8_BL3310_P3
Thu group only
Friday
16-03-2018
10:00 to 17:00
Chemistry
Purdie Lab
Dr Jacqueline Nairn

Practical P4: Characterisation of mitochondrial complexes
2017-8_BL3310_P4
Fri group only

Reading Week: 17-Mar-2018 to 01-Apr-2018

Semester 2: Week 8

DATE & TIMEVENUESTAFFEVENT
Tuesday
03-04-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Samantha Pitt

Lecture L20: Mitochondrial Transporters
2017-8_BL3310_L20
Wednesday
04-04-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Jacqueline Nairn

Lecture L21: Intro to Lab 3
2017-8_BL3310_L21
Thursday
05-04-2018
10:00 to 13:00
Chemistry
Purdie Lab
Dr Jacqueline Nairn

Practical P5: Seahorse
2017-8_BL3310_P5
Bring laptop to workshop - Thu group only
Friday
06-04-2018
10:00 to 13:00
Chemistry
Purdie Lab
Dr Jacqueline Nairn

Practical P6: Seahorse
2017-8_BL3310_P6
Bring laptop to workshop - Fri group only

Semester 2: Week 9

DATE & TIMEVENUESTAFFEVENT
Monday
09-04-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Jacqueline Nairn

Lecture L22: Mitochondria and cell death
2017-8_BL3310_L22
Tuesday
10-04-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr John Lucocq

Lecture L23: Mitochondria and parasitic infection
2017-8_BL3310_L23
Wednesday
11-04-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Rona Ramsay

Lecture L24: Mitochondrial dynamics, fission and fusion
2017-8_BL3310_L24

Semester 2: Week 10

DATE & TIMEVENUESTAFFEVENT
Monday
16-04-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Prof Frank Gunn-Moore

Lecture L25: Mitochondria & disease I
2017-8_BL3310_L25
Tuesday
17-04-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Prof Frank Gunn-Moore

Lecture L26: Mitochondria & disease II
2017-8_BL3310_L26
Wednesday
18-04-2018
12:00 to 13:00
Biomolecular Sciences Building
Lecture Theatre
Dr Jacqueline Nairn

Workshop W1: Revision workshop
2017-8_BL3310_W1

Semester 2: Week 11

DATE & TIMEVENUESTAFFEVENT
Thursday
26-04-2018
14:00 to 17:00
Biomolecular Sciences Building
Lecture Theatre
Dr Jacqueline Nairn
Dr Rona Ramsay
Other O2: STUDENT PRESENTATIONS
2017-8_BL3310_O2
All students attend
Friday
27-04-2018
14:00 to 17:00
Biomolecular Sciences Building
Lecture Theatre
Dr Jacqueline Nairn
Dr Rona Ramsay
Other O3: STUDENT PRESENTATIONS
2017-8_BL3310_O3
All students attend
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL3310: Reading List

Click for BL3310 reading list

BL3310: Assessment

3-hour Written Examination = 66%, Coursework = 34%*

Assessment:
Practical Lab Book
Due by:
26/02/2018 12:00
Feedback due by:
19/03/2018 12:00
Type:
Paper Hand-in
Weight:
0%
Assessment:
Practical Report and Lab Book
Due by:
03/04/2018 12:00
Feedback due by:
24/04/2018 12:00
Type:
Turnitin
Weight:
58.8%
Assessment:
Seahorse workshop
Due by:
09/04/2018 12:00
Feedback due by:
30/04/2018 12:00
Type:
Turnitin
Weight:
0%
Assessment:
Presentation
Due by:
26/04/2018 12:00
Feedback due by:
17/05/2018 12:00
Type:
Turnitin
Weight:
41.2%

(MMS assessment data cached: 28 March 2018 22:20:20.)


The following related information applies to all Biology modules:

School of Biology Marking Criteria: See School of Biology Undergraduate Handbook
Late submission of continuous assessment work:

All late submissions of coursework that do not require electronic submission should be made via the late submissions box in the Biomolecular Science Building (beside the Teaching Office)
Exam details: See School of Biology Undergraduate Handbook
Exam timetable: see http://www.st-andrews.ac.uk/students/academic/examinations/examtimetablescurrent/
Expected attendance: See School of Biology Undergraduate Handbook for detailed attendance requirements.
Good Academic Practice & Avoiding Academic Misconduct: See School of Biology Undergraduate Handbook
University Student Handbook: University Student Handbook
School and University regulations in the School and University Undergraduate Handbook relating to absence reporting, penalties and rules for late submission of work, extensions for coursework, return of coursework, S-coding, good academic practice and Academic Alerts.: School of Biology Undergraduate Handbook University Student Handbook
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

Who to ask

(Information in this section applies to all Biology Modules)

Questions about different aspects of the module should be directed to different people:

Questions about Contact
General teaching matters Biology Teaching Office ( bioteach@st-andrews.ac.uk )
Rescheduled or cancelled events Check your University email
Lecture or practical content The lecturer who presented the material
Completing assessed practical assignments The lecturer who set the assignment
Completing assessments Module Organiser (Dr Jacqueline Nairn jn37@st-andrews.ac.uk)
Marking on continuous assessment The Demonstrator or Module Organiser (Dr Jacqueline Nairn jn37@st-andrews.ac.uk)
Marking on exams Module Organiser (Dr Jacqueline Nairn jn37@st-andrews.ac.uk)
Rearranging practical days Grant Brown
Absence and/or extensions Module Organiser (Dr Jacqueline Nairn jn37@st-andrews.ac.uk) and the Biology Teaching Office ( bioteach@st-andrews.ac.uk )

Difficulties with academic progress which impact more than one module:

Year Coordinator

See School of Biology Undergraduate student handbook for list: http://biology.st-andrews.ac.uk/documents/UndergraduateHandbook.pdf

Overall performance, progress or future directions:

Advisor of Studies

Disability:

Disability Coordinator (Dr Jacqueline Nairn jn37@st-andrews.ac.uk)

Biology Teaching Office:

The Biology Hive, New Technology Centre, University of St Andrews, North Haugh, St Andrews, Fife KY16 9SR

Email: bioteach@st-andrews.ac.uk

Tel: 01334 463602

BL3310: Contributing Staff

Dr Jacqueline Nairn
(Module Organiser)

Senior Lecturer (Education Focused)jn37@st-andrews.ac.uk
Dr Rafael Guimaraes da SilvaDr Rafael Guimaraes da SilvaResearch Fellowrgds@st-andrews.ac.uk
Prof Frank Gunn-MooreProf Frank Gunn-MooreProfessor of Molecular Neurobiology fjg1@st-andrews.ac.uk
Prof Peter HeathcoteProfessor, Visiting Scholarph28@st-andrews.ac.uk
Dr John LucocqDr John LucocqReaderjml7@st-andrews.ac.uk
Dr Jacqueline Nairn
(Module Organiser)
Senior Lecturer (Education Focused)jn37@st-andrews.ac.uk
Dr Samantha PittDr Samantha PittRoyal Society of Edinburgh Biomedical Fellowsjp24@st-andrews.ac.uk
Dr Gerald PrescottSenior Lecturergrp2@st-andrews.ac.uk
Dr Rona RamsayDr Rona RamsayReaderrrr@st-andrews.ac.uk
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL3310: Learning Outcomes

The conversion of one form of energy into another by a biochemical process is at the centre of all life.

Students completing module BL3310 successfully should be able to:

  • To develop an understanding of how biological systems conserve energy from food oxidation & light absorption (photosynthesis), and the conversion of the resulting redox energy into chemical energy
  • To build an appreciation of the electron transfer processes in biology and the energetics of transport processes
  • To examine in detail the principles of and evidence for the the chemiosmotic theory and its principles including the structure and function of electron and proton transfer systems of energy transducing systems
  • To consider recently studied associations between mitochondria and disease
  • To introduce the methods used in this field of study
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL3310: Acquired Skills

Practical Skills

  • Biomolecule isolation/characterisation
  • Buffers
  • Enzyme assay
  • Pipetting
  • Protein characterisation

Transferable Skills

  • Short group presentation on given topic (up to 15 min)
  • "Short" practical write-up (e.g. completed worksheet)
  • Critically evaluating sources/information
  • Finding literature
  • Lab safety awareness
  • Problem-solving questions
  • Calculations/equations
  • Dilutions
  • Produce tables
  • Lab or field notebook
  • Designing experiments
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

Policies

(Information in this section applies to all Biology Modules)