School of Biology current student

Information for current students at the School of Biology

Biology Online Module Handbook

BL2306 Biochemistry

(BL2306 online module handbook version 133)

cover image
Due to recent technological developments, metabolism and its regulation has re-emerged as an important area of Biology. This module will examine major biological macromolecules, the common motifs which occur in metabolic reactions, explore the properties of enzymes catalysing these reactions and consider the approaches to characterise the small molecule complement (metabolites) of biological systems. A number of central metabolic pathways and their control will be studied in detail, alongside examples of their importance in disease and recent metabolomic studies.*

Credits: 15*

Semester: 2

Module Organiser
Dr Jacqueline Nairn
jn37@st-andrews.ac.uk
01334 463604
Pre-requisite Modules:
Before taking this module you must pass BL1101 and pass BL1102*
Anti-requisite Modules:
*
Post-requisite Modules:
*
Additional Module Information:


Biology Teaching Office:
Level 2, Biomolecular Sciences Building, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST

Email: bioteach@st-andrews.ac.uk      Phone: +44 (0)1334 46 3602 or 3566

BL2306: Timetable

Legend (not all modules have every event type):
lecture
tutorial
workshop
practical
other

Semester 2: Week 1

DATE & TIMEVENUESTAFFEVENT
Monday
15-01-2024
14:00 to 17:00
Biomolecular Sciences Building
Teaching Lab A
Dr Jacqueline Nairn
Mr Duncan Laird
Mr Christopher Simmons-Riach
Mr Alasdair Stenhouse
Practical P1: Practical 1 - Module Introduction and Lab Skills
2023-4_BL2306_P1
Lab Group A
Tuesday
16-01-2024
14:00 to 17:00
Biomolecular Sciences Building
Teaching Lab A
Dr Jacqueline Nairn
Mr Duncan Laird
Mr Christopher Simmons-Riach
Mr Alasdair Stenhouse
Practical P2: Practical 1 - Module Introduction and Lab Skills
2023-4_BL2306_P2
Lab Group B
Thursday
18-01-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Tracey Gloster
-
Lecture L1: The building blocks of life I
2023-4_BL2306_L1
Friday
19-01-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Tracey Gloster
-
Lecture L2: The building blocks of life II
2023-4_BL2306_L2

Semester 2: Week 2

DATE & TIMEVENUESTAFFEVENT
Wednesday
24-01-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Tracey Gloster
-
Lecture L3: The building blocks of life III
2023-4_BL2306_L3
Thursday
25-01-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Tracey Gloster
-
Lecture L4: The building blocks of life IV
2023-4_BL2306_L4
Friday
26-01-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Tracey Gloster
-
Lecture L5: Introduction to Practical 2 Visualising Molecules
2023-4_BL2306_L5

Semester 2: Week 3

DATE & TIMEVENUESTAFFEVENT
Monday
29-01-2024
14:00 to 17:00
Biomolecular Sciences Building
Teaching Lab A
Dr Tracey Gloster
Mr Duncan Laird
Mr Christopher Simmons-Riach
Mr Alasdair Stenhouse
Practical P3: Practical 2 - Visualising Molecules
2023-4_BL2306_P3
Lab Group A. Please bring laptops
Tuesday
30-01-2024
14:00 to 17:00
Biomolecular Sciences Building
Teaching Lab A
Dr Tracey Gloster
Mr Duncan Laird
Mr Christopher Simmons-Riach
Mr Alasdair Stenhouse
Practical P4: Practical 2 - Visualising Molecules
2023-4_BL2306_P4
Lab Group B. Please bring laptops
Thursday
01-02-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Tracey Gloster
-
Lecture L6: The building blocks of life V
2023-4_BL2306_L6
Friday
02-02-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Tracey Gloster
-
Lecture L7: Revision - the building blocks of life
2023-4_BL2306_L7

Semester 2: Week 4

DATE & TIMEVENUESTAFFEVENT
Wednesday
07-02-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Rafael Guimaraes da Silva
-
Lecture L8: Enzyme kinetics I
2023-4_BL2306_L8
Thursday
08-02-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Rafael Guimaraes da Silva
-
Lecture L9: Enzyme kinetics II
2023-4_BL2306_L9
Friday
09-02-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Jacqueline Nairn
-
Lecture L10: Introduction to Practical 3 - Enzyme kinetics
2023-4_BL2306_L10

Semester 2: Week 5

DATE & TIMEVENUESTAFFEVENT
Monday
12-02-2024
14:00 to 17:00
Biomolecular Sciences Building
Teaching Lab A
Dr Jacqueline Nairn
Mr Duncan Laird
Mr Christopher Simmons-Riach
Mr Alasdair Stenhouse
Practical P5: Practical 3 -Enzyme kinetics
2023-4_BL2306_P5
Lab Group A. Please bring laptops
Tuesday
13-02-2024
14:00 to 17:00
Biomolecular Sciences Building
Teaching Lab A
Dr Jacqueline Nairn
Mr Duncan Laird
Mr Christopher Simmons-Riach
Mr Alasdair Stenhouse
Practical P6: Practical 3 -Enzyme kinetics
2023-4_BL2306_P6
Lab Group B. Please bring laptops
Thursday
15-02-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Rafael Guimaraes da Silva
-
Lecture L11: Enzyme kinetics III
2023-4_BL2306_L11
Friday
16-02-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Rafael Guimaraes da Silva
-
Lecture L12: Enzymes: Mechanism of Action
2023-4_BL2306_L12

Semester 2: Week 6

DATE & TIMEVENUESTAFFEVENT
Wednesday
21-02-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Rafael Guimaraes da Silva
-
Lecture L13: Revision - Enzyme Kinetics
2023-4_BL2306_L13
Thursday
22-02-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Jacqueline Nairn
-
Lecture L14: Metabolic Control Strategies I
2023-4_BL2306_L14
Friday
23-02-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Tracey Gloster
Dr Carolin Kosiol
Lecture L15: Introduction to Practical 4 Lysozyme Study
2023-4_BL2306_L15

Spring Break: 26-Feb-2024 to 01-Mar-2024

Semester 2: Week 7

DATE & TIMEVENUESTAFFEVENT
Monday
04-03-2024
14:00 to 17:00
Biomolecular Sciences Building
Teaching Lab A
Dr Tracey Gloster
Dr Carolin Kosiol
Practical P7: Practical 4 - Lysozyme Study
2023-4_BL2306_P7
Lab Group A. Please bring laptops
Tuesday
05-03-2024
14:00 to 17:00
Biomolecular Sciences Building
Teaching Lab A
Dr Tracey Gloster
Dr Carolin Kosiol
Practical P8: Practical 4 - Lysozyme Study
2023-4_BL2306_P8
Lab Group B. Please bring laptops
Thursday
07-03-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Jacqueline Nairn
-
Lecture L16: Metabolic Control Strategies II
2023-4_BL2306_L16
Friday
08-03-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Jacqueline Nairn
-
Lecture L17: Metabolic Control Activity
2023-4_BL2306_L17

Semester 2: Week 8

DATE & TIMEVENUESTAFFEVENT
Wednesday
13-03-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Jacqueline Nairn
-
Lecture L18: Glycolysis and Gluconeogenesis
2023-4_BL2306_L18
Thursday
14-03-2024
09:00 to 10:00
Online
online
Dr Jacqueline Nairn
-
Lecture L19: Link between Glycolysis and TCA
2023-4_BL2306_L19
Recording & slides on Moodle
Friday
15-03-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Jacqueline Nairn
-
Lecture L20: Introduction to Practical 5 - Protein purification
2023-4_BL2306_L20

Semester 2: Week 9

DATE & TIMEVENUESTAFFEVENT
Monday
18-03-2024
14:00 to 17:00
Biomolecular Sciences Building
Teaching Lab A
Dr Jacqueline Nairn
Dr Shirley Graham
Practical P9: Practical 5 - Protein purification
2023-4_BL2306_P9
Lab Group A. Please bring laptops.
Tuesday
19-03-2024
14:00 to 17:00
Biomolecular Sciences Building
Teaching Lab A
Dr Jacqueline Nairn
Dr Shirley Graham
Practical P10: Practical 5 - Protein purification
2023-4_BL2306_P10
Lab Group B. Please bring laptops.
Thursday
21-03-2024
09:00 to 10:00
Other

-
Lecture L21: NO LECTURE
2023-4_BL2306_L21
Friday
22-03-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Jacqueline Nairn
-
Lecture L22: TCA and ETC
2023-4_BL2306_L22

Semester 2: Week 10

DATE & TIMEVENUESTAFFEVENT
Wednesday
27-03-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Jacqueline Nairn
-
Lecture L23: Fatty Acid Metabolism and Metabolism Revision
2023-4_BL2306_L23
Thursday
28-03-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Rafael Guimaraes da Silva
-
Lecture L24: Purine/Pyrimidine Metabolism I
2023-4_BL2306_L24
Friday
29-03-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Rafael Guimaraes da Silva
-
Lecture L25: Purine/Pyrimidine Metabolism II
2023-4_BL2306_L25

Semester 2: Week 11

DATE & TIMEVENUESTAFFEVENT
Monday
01-04-2024
14:00 to 17:00
Biomedical Sciences Building
Teaching Lab A
Dr Jacqueline Nairn
Dr Shirley Graham
Practical P11: Practical 6 - SDS PAGE
2023-4_BL2306_P11
Lab Group A. Please bring your laptop
Tuesday
02-04-2024
14:00 to 17:00
Biomolecular Sciences Building
Teaching Lab A
Dr Jacqueline Nairn
Dr Shirley Graham
Practical P12: Practical 6 - SDS PAGE
2023-4_BL2306_P12
:ab Group B. Please bring your laptop
Thursday
04-04-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Rafael Guimaraes da Silva
-
Lecture L26: Amino acid metabolism
2023-4_BL2306_L26
Friday
05-04-2024
09:00 to 10:00
Willie Russell Laboratories
Lecture Room B
Dr Rafael Guimaraes da Silva
Dr Jacqueline Nairn
Lecture L27: Revision of RGdS material & BL2306 exam preparation
2023-4_BL2306_L27
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL2306: Assessment

2-hour Written Examination = 50%, Coursework = 50%*

The following related information applies to all Biology modules:

School of Biology Marking Criteria: See JH booklet info (st-andrews.ac.uk) 
Late submission of continuous assessment work:

All late submissions of coursework that do not require electronic submission should be made via the Biology Teaching Office, Level 2, BMS Building, North Haugh.
Exam details: See School of Biology UG Handbook JH booklet info (st-andrews.ac.uk)  : All Biology exams will be conducted online for 2022-23.
Exam timetable: See Timetables - Exams - University of St Andrews (st-andrews.ac.uk) 
Expected attendance: See JH booklet info (st-andrews.ac.uk)  for detailed attendance requirements.
Good Academic Practice & Avoiding Academic Misconduct: See JH booklet info (st-andrews.ac.uk)
University Student Handbook: University Student Handbook
School and University regulations in the School and University Undergraduate Handbook relating to absence reporting, penalties and rules for late submission of work, extensions for coursework, return of coursework, S-coding, good academic practice and Academic Alerts.: JH booklet info (st-andrews.ac.uk)
University Student Handbook
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

Who to ask

(Information in this section applies to all Biology Modules)

Before contacting staff, students should check the content of the Biology Undergraduate Handbook, the module handbook and specific task instructions.

Questions about Contact
General teaching matters Biology Teaching Office ( bioteach@st-andrews.ac.uk )
Rescheduled or cancelled events Check your University email
Lecture or practical content The lecturer who presented the material
Completing assessed practical assignments The lecturer who set the assignment
Completing assessments Module Organiser (Dr Jacqueline Nairn jn37@st-andrews.ac.uk)
Marking on continuous assessment The Demonstrator or Module Organiser (Dr Jacqueline Nairn jn37@st-andrews.ac.uk)
Marking on exams Module Organiser (Dr Jacqueline Nairn jn37@st-andrews.ac.uk)
Rearranging practical days
Module Organiser (Dr Jacqueline Nairn jn37@st-andrews.ac.uk)
Absence and/or extensions Module Organiser (Dr Jacqueline Nairn jn37@st-andrews.ac.uk)

and the Biology Teaching Office ( bioteach@st-andrews.ac.uk )

Difficulties with academic progress which impact more than one module:

Year Coordinator

See School of Biology UG Handbook for list:
JH booklet info (st-andrews.ac.uk)

Overall performance, progress or future directions:

Advisor of Studies

Disability:

Disability Coordinator ( biodisabilities@st-andrews.ac.uk )

For advice and support on any issue e.g. academic, financial, international, personal or health matters, or if you are unsure of who to go to for help:

Advice & Support Centre

Address: 79 North Street, St Andrews

Email: theasc@st-andrews.ac.uk

Web: https://www.standrews.ac.uk/ask-a-question/

Tel: 01334 462020

University assistance with urgent matters out of office hours:

Tel: 01334 476161

Web: https://www.st-andrews.ac.uk/students/advice/counselling/incrisis/

Biology Teaching Office:

We are happy to hear from you about teaching matters. The School of Biology Teaching Office is open Monday to Friday 09.00 - 13.00 and 14.00 - 17.00. School of Biology staff will respond to your emails during these hours. Our team will provide a response to you within three working days.

Biology Teaching Office (Level 2), University of St Andrews, Biomolecular Sciences Building, North Haugh, St Andrews, Fife KY16 9ST

Email: bioteach@st-andrews.ac.uk

Tel: 01334 46 3602 or 3566

BL2306: Contributing Staff

Dr Jacqueline Nairn
(Module Organiser)

Senior Lecturer jn37@st-andrews.ac.uk
Dr Tracey GlosterReadertmg@st-andrews.ac.uk
Dr Shirley GrahamResearch Fellowsg71@st-andrews.ac.uk
Dr Rafael Guimaraes da SilvaResearch Fellowrgds@st-andrews.ac.uk
Dr Carolin KosiolReaderck202@st-andrews.ac.uk
Mr Duncan LairdTeaching Laboratory Techniciandsl6@st-andrews.ac.uk
Dr Jacqueline Nairn
(Module Organiser)
Senior Lecturer jn37@st-andrews.ac.uk
Mr Christopher Simmons-RiachTechniciancsr5@st-andrews.ac.uk
Mr Alasdair StenhouseLaboratory Teaching Technicianajs3@st-andrews.ac.uk
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL2306: Learning Outcomes

Students completing module BL2306 successfully should be able to:

  • Explain the chemistry and structure of the major biological macromolecules and how that determines their biological properties
  • Mine, manipulate and interpret data from small molecule and macromolecular databases
  • Use molecular viewers
  • Explain the chemical and thermodynamic principles underlying biological catalysis and the role of enzymes and other proteins in determining the function and fate of cells and organisms
  • Conduct experiments to explore enzyme activity
  • Demonstrate a critical understanding of essential features of cell metabolism and its control, including topics such as energy and signal transduction, respiration and photosynthesis
  • Appreciate the diversity of small molecules within cells, their dynamic concentration range and how to study these, both individually and as part of a metabolome
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL2306: Acquired Skills

Practical Skills

  • Biomolecule isolation/characterisation
  • Buffers
  • Chromatography
  • Database interogation
  • Enzyme assay
  • Kinetic data analysis
  • Molecular viewer software
  • Pipetting
  • Protein characterisation
  • Protein purification
  • Protein quantitation

Transferable Skills

  • Preparing group poster on given topic
  • Q+A poster session
  • "Full" practical write-up (Intro, Methods, Results, Discussion)
  • "Short" practical write-up (e.g. completed worksheet)
  • Handout (for presentation or poster)
  • Critically evaluating sources/information
  • Finding information on the web
  • Finding literature
  • Referencing
  • Searching databases
  • Sourcing figures/tables
  • Lab safety awareness
  • Problem-solving questions
  • Calculations/equations
  • Concentrations
  • Data analysis
  • Data presentation
  • Dilutions
  • Draw a line of best fit
  • Produce graphs/figures
  • Produce tables
  • SI units
  • Use Excel
  • Use R or R Studio
  • Working in pairs/small groups
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

Policies

(Information in this section applies to all Biology Modules)

  • The procedures and regulations followed by the School of Biology are outlined in the University Handbook and in the School of Biology UG handbook  JH booklet info (st-andrews.ac.uk) 
  • All coursework associated with the module must be completed and submitted by its due date.
  • Specific School regulations relating to absence reporting, penalties and rules for late submission of work, extensions for coursework, return of coursework, S-coding, Good Academic Practice and Academic Alert are stated in the School of Biology UG hand book JH booklet info (st-andrews.ac.uk)  and students are required to carefully read these regulations.
  • Students are also referred to the University Handbook, available at: http://www.st-andrews.ac.uk/studenthandbook/