Biology Online Module Handbook

BL2302 Molecular Biology

(BL2302 online module handbook version 14)

cover image
Molecular biology is an essential tool within modern biology, widely used in biochemistry, cell biology and ecology. This module will provide an introduction to modern molecular biology. Lectures will cover fundamental biological processes such as transcription, translation, DNA replication and repair - as well as touch on the genomics revolution and how this has influenced the field. These concepts will be reinforced through laboratory practical classes where students will develop their practical skills and be exposed to the use of basic bioinformatics resources to analyse and interpret data.*

Credits: 15*

Semester: 1

Module Organiser
Dr Helder Ferreira
hcf2@st-andrews.ac.uk
01334 463425
Pre-requisite Modules:
BEFORE TAKING THIS MODULE YOU SHOULD PASS BL1101 AND PASS BL1102. BEFORE TAKING THIS MODULE YOU MUST PASS BL1101 AND PASS BL1102*
Anti-requisite Modules:
IN TAKING THIS MODULE YOU CANNOT TAKE BL2104. IN TAKING THIS MODULE YOU CANNOT TAKE BL2104*
Post-requisite Modules:
BL3301, BL3302, BL3310, BL3315, BL3322*
Additional Module Information:
Please check MMS regularly for additional module information


Biology Teaching Office:
Room 1.17, Biomolecular Sciences Building, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST

Email: bioteach@st-andrews.ac.uk      Tel: 01334  463602

BL2302: Timetable

Legend (not all modules have every event type):
lecture
tutorial
workshop
practical
other

Semester 1: Week 1

DATE & TIMEVENUESTAFFEVENT
Thursday
21-09-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Helder Ferreira

Lecture L1: Introduction to molecular biology
2017-8_BL2302_L1
Friday
22-09-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Stuart MacNeill

Lecture L2: DNA structure and sequencing
2017-8_BL2302_L2

Semester 1: Week 2

DATE & TIMEVENUESTAFFEVENT
Monday
25-09-2017
14:00 to 17:00
Purdie Building
Purdie Teaching Lab
Dr Helder Ferreira

Practical P1: Basic lab skills
2017-8_BL2302_P1
Tuesday
26-09-2017
14:00 to 17:00
Purdie Building
Purdie Teaching Lab
Dr Helder Ferreira

Practical P2: Basic lab skills
2017-8_BL2302_P2
Wednesday
27-09-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Stuart MacNeill

Lecture L3: Genome structure and sequencing
2017-8_BL2302_L3
Thursday
28-09-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Stuart MacNeill

Lecture L4: DNA replication
2017-8_BL2302_L4
Friday
29-09-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Stuart MacNeill

Lecture L5: DNA replication
2017-8_BL2302_L5

Semester 1: Week 3

DATE & TIMEVENUESTAFFEVENT
Thursday
05-10-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Helder Ferreira

Lecture L6: Transcription
2017-8_BL2302_L6
Friday
06-10-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Helder Ferreira

Lecture L7: Transcription
2017-8_BL2302_L7

Semester 1: Week 4

DATE & TIMEVENUESTAFFEVENT
Monday
09-10-2017
11:00 to 14:00
Mathematical Institute
Maths Computer Classroom
Dr Helder Ferreira

Practical P3: Basic bioinformatics - DNA sequence handling
2017-8_BL2302_P3
assessed practical
Tuesday
10-10-2017
11:00 to 14:00
Mathematical Institute
Maths Computer Classroom
Dr Helder Ferreira

Practical P4: Basic bioinformatics - DNA sequence handling
2017-8_BL2302_P4
assessed practical
Wednesday
11-10-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Helder Ferreira

Lecture L8: Transcription
2017-8_BL2302_L8
Thursday
12-10-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Helder Ferreira

Lecture L9: Gene regulation & regulatory RNAs
2017-8_BL2302_L9
Friday
13-10-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Prof Malcolm White

Lecture L10: DNA damage and direct repair
2017-8_BL2302_L10

Semester 1: Week 5

DATE & TIMEVENUESTAFFEVENT
Thursday
19-10-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Prof Malcolm White

Lecture L11: Excision Repair
2017-8_BL2302_L11
Friday
20-10-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Prof Malcolm White

Lecture L12: Mismatch Repair and Double strand break repair
2017-8_BL2302_L12

Semester 1: Week 7

DATE & TIMEVENUESTAFFEVENT
Monday
30-10-2017
14:00 to 17:00
Purdie Building
Purdie Teaching Lab
Dr Stuart MacNeill

Practical P5: PCR
2017-8_BL2302_P5
Tuesday
31-10-2017
14:00 to 17:00
Purdie Building
Purdie Teaching Lab
Dr Stuart MacNeill

Practical P6: PCR
2017-8_BL2302_P6
Thursday
02-11-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Helder Ferreira

Other O1: mid-module test
2017-8_BL2302_O1
assessed via Moodle
Friday
03-11-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Prof Martin Ryan

Lecture L13: Translation
2017-8_BL2302_L13

Semester 1: Week 8

DATE & TIMEVENUESTAFFEVENT
Wednesday
08-11-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Prof Martin Ryan

Lecture L14: Translation
2017-8_BL2302_L14
Thursday
09-11-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Prof Martin Ryan

Lecture L15: Translation
2017-8_BL2302_L15
Friday
10-11-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Prof Martin Ryan

Lecture L16: Translational control
2017-8_BL2302_L16

Semester 1: Week 9

DATE & TIMEVENUESTAFFEVENT
Monday
13-11-2017
14:00 to 17:00
Purdie Building
Purdie Teaching Lab
Dr Stuart MacNeill

Practical P7: Plasmid purification and restriction digest
2017-8_BL2302_P7
Tuesday
14-11-2017
14:00 to 17:00
Purdie Building
Purdie Teaching Lab
Dr Stuart MacNeill

Practical P8: Plasmid purification and restriction digest
2017-8_BL2302_P8
Thursday
16-11-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Stuart MacNeill

Lecture L17: Transposition
2017-8_BL2302_L17
Friday
17-11-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Stuart MacNeill

Lecture L18: Genomics
2017-8_BL2302_L18

Semester 1: Week 10

DATE & TIMEVENUESTAFFEVENT
Wednesday
22-11-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Stuart MacNeill

Lecture L19: Review of minipreps and PCR
2017-8_BL2302_L19
Thursday
23-11-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Helder Ferreira

Lecture L20: Tools and techniques in molecular biology
2017-8_BL2302_L20
Friday
24-11-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Helder Ferreira

Lecture L21: Tools and techniques in molecular biology
2017-8_BL2302_L21

Semester 1: Week 11

DATE & TIMEVENUESTAFFEVENT
Monday
27-11-2017
14:00 to 17:00
Purdie Building
Purdie Teaching Lab
Dr Helder Ferreira

Practical P9: Inducing and measuring YFP expression
2017-8_BL2302_P9
Tuesday
28-11-2017
14:00 to 17:00
Purdie Building
Purdie Teaching Lab
Dr Helder Ferreira

Practical P10: Inducing and measuring YFP expression
2017-8_BL2302_P10
Thursday
30-11-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Prof Malcolm White

Lecture L22: Origins of molecular biology (Module wrap-up)
2017-8_BL2302_L22
Friday
01-12-2017
09:00 to 10:00
Purdie Building
Purdie Lecture Theatre B
Dr Helder Ferreira

Lecture L23: Exam preparation/feedback
2017-8_BL2302_L23
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL2302: Reading List

Click for BL2302 reading list

BL2302: Assessment

2-hour Written Examination = 50%, Coursework = 50%*

Assessment:
Practical PSQ
Due by:
20/10/2017 17:00
Feedback due by:
03/11/2017 17:00
Type:
Single Upload
Weight:
60%

(MMS assessment data cached: 17 November 2017 23:20:14.)


The following related information applies to all Biology modules:

School of Biology Marking Criteria: See School of Biology Undergraduate Handbook
Late submission of continuous assessment work:

All late submissions of coursework that do not require electronic submission should be made via the late submissions box in the Biomolecular Science Building (beside the Teaching Office)
Exam details: See School of Biology Undergraduate Handbook
Exam timetable: see http://www.st-andrews.ac.uk/students/academic/examinations/examtimetablescurrent/
Expected attendance: See School of Biology Undergraduate Handbook for detailed attendance requirements.
Good Academic Practice & Avoiding Academic Misconduct: See School of Biology Undergraduate Handbook
University Student Handbook: University Student Handbook
School and University regulations in the School and University Undergraduate Handbook relating to absence reporting, penalties and rules for late submission of work, extensions for coursework, return of coursework, S-coding, good academic practice and Academic Alerts.: School of Biology Undergraduate Handbook University Student Handbook
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

Who to ask

(Information in this section applies to all Biology Modules)

Questions about different aspects of the module should be directed to different people:

Questions about Contact
General teaching matters Biology Teaching Office ( bioteach@st-andrews.ac.uk )
Rescheduled or cancelled events Check your University email
Lecture or practical content The lecturer who presented the material
Completing assessed practical assignments The lecturer who set the assignment
Completing assessments Module Organiser (Dr Helder Ferreira hcf2@st-andrews.ac.uk)
Marking on continuous assessment The Demonstrator or Module Organiser (Dr Helder Ferreira hcf2@st-andrews.ac.uk)
Marking on exams Module Organiser (Dr Helder Ferreira hcf2@st-andrews.ac.uk)
Rearranging practical days Grant Brown
Absence and/or extensions Module Organiser (Dr Helder Ferreira hcf2@st-andrews.ac.uk) and the Biology Teaching Office ( bioteach@st-andrews.ac.uk )

Difficulties with academic progress which impact more than one module:

Year Coordinator

See School of Biology Undergraduate student handbook for list: http://biology.st-andrews.ac.uk/documents/UndergraduateHandbook.pdf

Overall performance, progress or future directions:

Advisor of Studies

Disability:

Disability Coordinator (Dr Jacqueline Nairn jn37@st-andrews.ac.uk)

Biology Teaching Office:

Room 1.17, Biomolecular Sciences Building, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST

Email: bioteach@st-andrews.ac.uk

Tel: 01334 463602

BL2302: Contributing Staff

Dr Helder Ferreira

Dr Helder Ferreira
(Module Organiser)

Lecturerhcf2@st-andrews.ac.uk
Dr Helder FerreiraDr Helder Ferreira
(Module Organiser)
Lecturerhcf2@st-andrews.ac.uk
Dr Stuart MacNeillDr Stuart MacNeillSULSA Reader in Translational Biologysam31@st-andrews.ac.uk
Prof Martin RyanProf Martin RyanProfessor of Translational Virologymdr1@st-andrews.ac.uk
Prof Malcolm WhiteProf Malcolm WhiteProfessormfw2@st-andrews.ac.uk
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL2302: Learning Outcomes

Students completing module BL2302 successfully should be able to:

  • Describe fundamental processes such as transcription, translation, DNA replication and repair
  • Develop an awareness of the genomics revolution and its impact on Biology
  • Develp practical skills in Molecular Biology
  • Develop skills required for Bioinformatic studies
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

BL2302: Acquired Skills

Practical Skills

  • Agarose gel
  • Buffers
  • DNA isolation
  • Handling microbes
  • Kinetic data analysis
  • Pipetting
  • Polymerase Chain Reaction (PCR)
  • Restriction digest

Transferable Skills

  • "Short" practical write-up (e.g. completed worksheet)
  • Searching databases
  • Generating questions
  • Lab safety awareness
  • Reflective analysis
  • Problem-solving questions
  • Calculations/equations
  • Data analysis
  • Data presentation
  • Use other data analysis software
  • Working in pairs/small groups
Data Sources: information in this online module handbook is gathered from several sources.
Small footnote marks beside content, or by section titles indicate the source.
* University of St Andrews Module Catalogue
School of Biology Symbiosis Database (module organisers only)
University of St Andrews MMS (St Andrews users only)

Policies

(Information in this section applies to all Biology Modules)